Standardized Antibiotic Regimen

For patients with sub-clinical or minimal evidence of endodontic infection:

  • Amoxicillin 875mg disp: (10), sig: BID until gone (or)
  • ‘Z-Pak#1’ as directed (for patients with a known penicillin allergy).

In more acutely symptomatic clinical situations involving moderate to severe discomfort either with or without swelling related to endodontic infection:

  • Augmentin 875mg disp: (20), sig: BID until gone followed by and/or with Flagyl (Metronidazole) 500mg disp: (21), sig: TID until gone (or)
  • Clindamycin 300mg disp: (21), sig: TID until gone (for patients with a known penicillin allergy) followed by (per symptom resolution) ‘Z-Pak#1’ as directed.

Antibiotic prophylaxis to minimize/prevent Infective Endocarditis:

  • Amoxicillin 2.0g one hour prior to dental procedure (or)
  • Azithromycin 500mg one hour prior to dental procedure (for patients with a known penicillin allergy)

Antibiotic prophylaxis to minimize/prevent bacterial infection of Joint Prosthesis:

  • Keflex (Cephalexin) 2.0g one hour prior to dental procedure (or)
  • Azithromycin 500mg one hour prior to dental procedure (for patients with a known penicillin allergy).